Program

 22/05 – Thursday – Room 1 – Adults – clinical track 
08:00 – 08:20 Opening session
08:20 – 08:50 Plenary lecture: Preventing, identifying, and managing sepsis in the community: research and clinical priorities
08:50 – 10:20 Thematic session : ‘Primary’ prevention – stopping sepsis occuring in the first place
08:50 – 09:05 One health: a growing concept
09:05 – 09:20 Can we modify the social determinants of health that influence the incidence (and outcome) of sepsis?
09:20 – 9:35 Can we prevent hospital-acquired sepsis with quality improvement?
9:35 – 9:50 Does anti-microbial resistance worsen the incidence or outcome of sepsis, and can we modify it?
9:50 – 10:20 Discussion
10:20 – 10:30 Interview : where are we with ‘fixing’ sepsis?
10:30 – 11:00 BREAK
11:00 – 12:30 Thematic session : ‘Secondary’ prevention – finding (and treating) sepsis before the patient is too sick
11:00 – 11:15 Lessons learned from pre-hospital systems to prevent or mitigate acute cardiac events
11:15 – 11:30 Where are we with ED and (non-ICU) hospital-based early sepsis detection and intervention programs?
11:30 – 11:45 Where are we with ICU-based early sepsis detection and intervention programs?
11:45  – 12:00 The future of sepsis detection and early warning systems
12:00 – 12:30 Discussion
12:30 – 14:00 LUNCH
12:30 – 13:30 Sponsors symposium
14:00 – 14:45 Round table : Diagnostic stewardship: How do to it better?
14:45 – 16:00 PRO-CON: Do we need more resuscitation studies in sepsis?
14:45 – 15:00 No, we just need to apply what we already know
15:00 – 15:15 Yes, we do not know what to do
15:15 – 15:30 Discussion
15:30 – 16:15 PRO-CON Do sepsis protocols improve antibiotic stewardship?
15:30 – 15:45 No, they just promote excess antibiotic use (and worse AMR)
15:45 – 16:00 Yes, they improve patient outcomes and reduce AMR
16:00 – 16:15 Discussion
16:15 – 16:45 BREAK
16:45 – 1800 Thematic session : The patient looks septic: what should you do first? And second?
16:45 – 17:00 Initial resuscitation in low resource settings
17:00 – 17:15 Is there a role for precision medicine ?
17:15 – 17:30 How early should we use vasopressin?
17:30 – 17:45 What’s the best way to determine severity of shock and adequacy or resuscitation?
17:45 – 18:00 Discussion
18:00 – 18:30 E-poster session
18:00 – 18:30 IQG Session
 22/05 – Thursday – Room 2 – Adults – clinical + multiprofessional track 
08:20 – 08:50 Conference: Making global ICU research democratic and inclusive
08:50 – 10:20 Thematic session: Implementing sepsis best practice guidelines
08:50 – 09:05 Barriers and solutions in private hospitals
09:05 – 09:20 Barriers and solutions in public hospitals
09:20 – 09:35 Action plans: how to get it right?
09:35 – 09:50 Alternative learning strategies
09:50 – 10:15 Discussion
10:15 – 10:30 Your question is my question
10:30 – 11:00 BREAK
11:00 – 12:15 Thematic session : Where are we going with clinical trials in sepsis?
11:00 – 11:15 Dealing with heterogeneity of treatment effect
11:15 – 11:30 Are plataform trials feasible in the global south?
11:30 – 11:45 What is the best way to randomize?
11:45 – 12:00 Is ‘live’ phenotyping possible in RCTs?
12:00 – 12:30 Discussion
12:30 – 14:00 LUNCH
12:30 – 13:30 Sponsors symposium
14:00 – 15:00 Round table : Ventilatory support: how can we do better?
15:00 – 16:15 Thematic session: Bugs, bugs, bugs …
15:00 – 15:15 Microbial landscape of Sepsis
15:15 – 15:30 Where are we in the great war of bugs vs humans?
15:30 – 15:45 Practice implications of BLING-3
15:45 – 16:00 Therapeutic drug monitoring: is it all hype?
16:00 – 16:15 Discussion
16:15 – 16:45 BREAK
16:45 – 17:05 Clinical challenge: Monitoring a patient with septic shock
17:05 – 18:00 PRO-CON: Antimicrobial resistance: how to solve this challenge?
17:05 – 17:20 We need better antimicrobials!
17:20 – 17:35 We need better prevention strategies!
17:35 – 18:00 Discussion
22/05 – Thursday  – Room 3 – Pediatrics and translational science
08:30 – 09:00Conference: How to define immune dysregulation in sepsis
09:00 – 10:30Thematic session : Immune dysregulation
09:00 – 09:15What can we learn from single-cell analyses?
09:15 – 09:30Trained immunity: Harnessing a potential double-edged sword in sepsis
09:30 – 09:45What is the role of neutrophils and NETs?
09:45 – 10:00What can we learn from proteomics?
10:00 – 10:30Discussion 
10:30 – 11:00BREAK
11:00 – 11:30Conference: Phoenix Sepsis Criteria – Is it an Advance?
11:30 – 12:30Round table: New sepsis definition: global relevance and tradeoffs 
12:30 – 14:00LUNCH
12:30 – 13:30Sponsors symposium 
14:00 – 14:30Conference: Phoenix Sepsis Criteria: How do we implement them at the bedside?
14:30 – 15:00PRO-CON: Septic Shock Management I 
14:30 – 14:45Steroids for septic shock: what is the downside?
14:45 – 15:00Steroids for septic shock: rarely meeded and likely harmful
15:00 – 15:15Discussion 
15:15 – 16:00PRO-CON: Septic Shock Management II
15:15 – 15:30Echocardiograms by POCUS should be standard
15:30 – 15:45POCUS: Echocardiograms by non-cardiologist can be risk
15:45 – 16:00Discussion 
16:00 – 16:15Interview: Pediatric Sepsis: Epidemiological Perspectives from Latin America, Spain, and Portugal
16:15 – 16:45BREAK
16:45 – 18:00Thematic session (pediatrics): Sepsis prevention, early detection and treatment      
16:45 – 17:00Effectiveness of vaccination in preventing sepsis
17:00 – 17:15Sepsis Biomarkers: Clinical Insights and Applications
17:15 – 17:30Fluids: How much, over what time, what type
17:30 – 17:45Early use of vasopressors – update on feasibility study
17:45 – 18:00Discussion 
23/05 – Friday -Room 1 – Adults – clinical track 
08:30 – 09:00Conference : When should we have Sepsis-4, and what should it look like?
09:00 – 10:30Thematic session : Shock persists after 24 hours: what next?
09:00 – 09:15Precision medicine with longitudinal shock phenotypes 
09:15 – 09:30Echocardiography: beyond the basics (discuss uncoupling,  LV outflow obstruction)
09:30 – 09:45Deaccumulation of fluids
09:45 – 10:00Modulating the dysregulated immune response
10:00 – 10:30Discussion 
10:30 – 11:00BREAK
11:00 – 12:30Thematic session :  The shock is over: why is my patient … 
11:00 – 11:15Not awake?
11:15 – 11:30Still requiring mechanical ventilation?
11:30 – 11:45Not tolerating tube feeds?
11:45 – 12:00Not making urine?
12:00 – 12:30Discussion 
12:30 – 14:00LUNCH
12:30 – 13:30Sponsors symposium 
14:00 – 14:25Challeging images: interactive session
14:25 – 14:45Your question is my question
14:45 – 15:45Round table : Improving survivorship from ED admission
15:45 – 16:15Conference:  AI-driven healthcare – promise and reality
16:15 – 16:45BREAK
16:45 – 18:15GRAND FINALE 
 23/05 – Friday – Adults – clinical + multiprofessional track 
08:30 – 09:00Plenary lecture: Re-examining the Host Response Hypothesis 30 years later
09:00 – 10:00Thematic session :  How can we improve engament of the heathcare team? 
09:00 – 09:15Multidisciplinar training: what are the challenges
09:15 – 09:30Nursing team: what can be done in the long term
09:30 – 09:45The patients perspective
09:45 – 10:00Discussion 
10:00 – 10:30Clinical challenge: how to improve long term outcomes
10:30 – 11:00BREAK
11:00 – 11:40Oral presentations  – Clinical science
11:40 – 12:30Round table :  Healhcare allies and the four pilars of sepsis management
12:30 – 14:00LUNCH
12:30 – 13:30Sponsors symposium 
14:00 – 15:10Thematic session : Thinking out of the box
14:00 – 14:15Can we go greener in sepsis care?
14:15 – 14:30Is the AI clinician our future?
14:30 – 14:45Reverse innovation: how creative solutions in low-resource settings will alter ICU care for everyone
14:45 – 15:10Discussion 
15:10 – 15:50Round table :What does ‘good’ quality improvement look like? Is it research? What ethical oversight does it require? 
15:50 – 16:15Plenary lecture  Revisiting organ dysfunction
16:15 – 16:45BREAK
16:45 – 18:00GRAND FINALE  (room 1)
 23/05 – Friday – Room 3 – Pediatrics and translational science
08:30 – 09:00plenaries in room 1 and 2
09:00 – 10:30Thematic session: Understanding the microbiota
09:00 – 09:15The gut microbiome in critical illness
09:15 – 09:30Empirical antibiotic therapy for sepsis: protect the anaerobic microbiota!
09:30 – 09:45Microbiota-Gut-Brain axis in sepsis
09:45 – 10:00Molecular insights of microbiota and innate lymphoid cell interactions
10:00 – 10:30Discussion 
10:30 – 11:00BREAK
11:00 – 11:40Oral presentations – translacional science
12:00 – 12:30Plenary lecture: Sepsis trials in children – challenges and opportunities
12:30 – 14:00LUNCH
12:40 – 13:30Sponsors symposium 
14:00 – 14:45Thematic session: Improving sepsis outcomes
14:00- 14::15Early recognition of sepsis in the community
14:15 – 14:30Sepsis protocol: Does it matter?
14:30 – 14:45Discussion 
14:45 – 15:15Clinical challenge: Still in shock: Navigating the next steps
15:15 – 16:15Thematic session :  Immunometabolism
15:15 – 15:30Metabolic regulation of immune function
15:30 – 15:45Rationale for cholesterol supplementation in sepsis
15:45 – 16:00Platelets and lipid metabolism
16:00 – 16:15Discussion 
16:15 – 16:45BREAK
16:45 – 18:00GRAND FINALE  (room 1)
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