| May 22nd – Thursday – Room 1 – Adults – clinical track | ||
| 08:00 – 08:20 | Opening session | |
| 08:20 – 08:50 | Conference: Preventing, identifying, and managing sepsis in the community: research and clinical priorities | Moderator: Luciano Azevedo Conferencist: Kathy Rowan |
| 08:50 – 10:20 | Thematic session : ‘Primary’ prevention – stopping sepsis occuring in the first place | Moderators: Daniela Souza and Derek Angus |
| 08:50 – 09:05 | Can vaccination reduce sepsis incidence? | Nancy Bellei |
| 09:05 – 09:20 | Can we modify the social determinants of health that influence the incidence (and outcome) of sepsis? | Fernando Bozza |
| 09:20 – 09:35 | Can we prevent sepsis with quality improvement? | Flávia Machado |
| 09:35 – 09:50 | Does anti-microbial resistance worsen the incidence or outcome of sepsis, and can we modify it? | Bruno Tomazini |
| 09:50 – 10:20 | Discussion | |
| 10:20 – 10:30 | Interview : where are we with ‘fixing’ sepsis? | Interviewer: Flávia Machado Interviewee: Derek Angus |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 12:30 | Thematic session : ‘Secondary’ prevention – finding (and treating) sepsis before the patient is too sick | Moderators: John Marshall and Luciano Azevedo |
| 11:00 – 11:15 | Lessons learned from pre-hospital systems to prevent or mitigate acute cardiac events | Christopher Seymour |
| 11:15 – 11:30 | Updated SOFA 2 score: what is new for sepsis? | Jorge Salluh |
| 11:30 – 11:45 | The future of sepsis detection and early warning systems | Rafael Moraes |
| 11:45 – 12:00 | AI and data science to evaluate sepsis outcomes: a perspective from low and middle income countries | Jorge Salluh |
| 12:00 – 12:30 | Discussion | |
| 12:30 – 13:30 | Baxter Satellite Symposium – Sepsis and Post-ICU Syndrome – The Critically Patient’s Journey SEE SYMPOSIUM | Luciano Azevedo e Debora Schujmann |
| 12:30 – 14:00 | LUNCH | |
| 12:30 – 13:30 | Sponsors symposium | |
| 14:00 – 14:45 | Round table: Diagnostic stewardship: How do to it better? | Moderators: Alexandre Biasi Debaters: Silvia Costa, Thierry Calandra, Joost Wiersinga, Tom van der Poll |
| 14:45 – 16:00 | PRO-CON: Do we need more resuscitation studies in sepsis? | Moderators: Fernando Ramos and Fernanda Attalah |
| 14:45 – 15:00 | No, we just need to apply what we already know | Derek Angus |
| 15:00 – 15:15 | Yes, we do not know what to do | Luciano Azevedo |
| 15:15 – 15:30 | Discussion | |
| 15:30 – 16:15 | PRO-CON Do sepsis protocols improve antibiotic stewardship? | Moderators: Fernando Ramos and Fernanda Attalah |
| 15:30 – 15:45 | No, they just promote excess antibiotic use (and worse AMR) | Mervyn Singer |
| 15:45 – 16:00 | Yes, they improve patient outcomes and reduce AMR | Flávia Machado |
| 16:00 – 16:15 | Discussion | |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 18:00 | Thematic session : The patient looks septic: what should you do first? And second? | Moderators: Mervyn Singer and Rafael Moraes |
| 16:45 – 17:00 | Initial resuscitation in low resource settings | Diptesh Aryal |
| 17:00 – 17:15 | Is there a role for precision medicine ? | Manu Shankar-Hari |
| 17:15 – 17:30 | Cristalloids: are they all the same? | Rafael Moraes |
| 17:30 – 17:45 | What’s the best way to determine adequacy or fluid resuscitation? | Fernando Ramos |
| 17:45 – 18:00 | Discussion | |
| 18:00 – 18:30 | E-poster session | |
| May 22nd – Thursday – Room 2 – Adults – clinical + multiprofessional track | ||
| 08:20 – 08:50 | Conference: Making global ICU research democratic and inclusive | Moderator: Rafael Moraes Conferencist: John Marshall |
| 08:50 – 10:20 | Thematic session: Implementing sepsis best practice guidelines | Moderators: Larissa Pellozo and Regis Rosa |
| 08:50 – 09:05 | Barriers and solutions in private hospitals | Alexandre Sete |
| 09:05 – 09:20 | Barriers and solutions in public hospitals | Mayra Ribeiro |
| 09:20 – 09:35 | Action plans: how to get it right? | Kathy Rowan |
| 09:35 – 09:50 | Alternative learning strategies | Diptesh Aryal |
| 09:50 – 10:15 | Discussion | |
| 10:15 – 10:30 | Your question is my question | Pedro Mendes and Viviane Veiga |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 12:15 | Thematic session : Where are we going with clinical trials in sepsis? | Moderators: Pedro Mendes and Viviane Veiga |
| 11:00 – 11:15 | Dealing with heterogeneity of treatment effect | Kathy Rowan |
| 11:15 – 11:30 | Are plataform trials feasible in the global south? | Alexandre Biasi |
| 11:30 – 11:45 | What is the best way to randomize? | Regis Rosa |
| 11:45 – 12:00 | Is ‘live’ phenotyping possible in RCTs? | Manu Shankar-Hari |
| 12:00 – 12:30 | Discussion | |
| 12:30 – 14:00 | LUNCH | |
| 12:30 – 13:30 | Sponsors symposium | |
| 14:00 – 15:00 | Round table : Healhcare team and the four pilars of sepsis management | Moderator: Thiago Lisboa Debaters: Josiane Ferreira, Vanessa D’Amaro, Giovanna Lorenzon, Alessandre Guimarães |
| 15:00 – 16:15 | Thematic session: Bugs, bugs, bugs … | Moderators: Matias Salomão and Bruno Tomazini |
| 15:00 – 15:15 | Microbial landscape of sepsis | Tom van der Poll |
| 15:15 – 15:30 | Where are we in the great war of bugs vs humans? | Ana Gales |
| 15:30 – 15:45 | Practice implications of BLING-3 | Thiago Lisboa |
| 15:45 – 16:00 | Therapeutic drug monitoring: is it all hype? | Carlos Kiffer |
| 16:00 – 16:15 | Discussion | |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 17:05 | Clinical challenge: Monitoring a patient with septic shock | Moderator: Alexandre Biasi Speaker: Bruno Besen |
| 17:05 – 18:00 | PRO-CON: Antimicrobial resistance: how to solve this challenge? | Moderator: Fernando Bozza |
| 17:05 – 17:20 | We need better antimicrobials! | Ana Gales |
| 17:20 – 17:35 | We need better prevention strategies! | Bruno Besen |
| 17:35 – 18:00 | Discussion | |
| May 22nd – Thursday – Room 3 – Pediatrics and translational science | ||
| 08:30 – 09:00 | Conference: How to define immune dysregulation in sepsis | Moderator: Reinaldo Salomão Conferencist: Tom van der Poll |
| 09:00 – 10:00 | Thematic session : Immune dysregulation | Moderators: Patricia Bozza and Reinaldo Salomão |
| 09:00 – 09:15 | What can we learn from single-cell analyses? | Manu Shankar-Hari |
| 09:15 – 09:30 | Trained immunity: Harnessing a potential double-edged sword in sepsis | Thierry Calandra |
| 09:30 – 09:45 | What is the role of neutrophils and NETs? | Fernando Cunha |
| 09:45 – 10:00 | What can we learn from proteomics? | Tom van der Poll |
| 10:00 – 10:30 | Discussion | |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 11:30 | Conference: Phoenix Sepsis Criteria – Is it an Advance? | Moderator: Daniela Souza Conferencist: Adrienne Randolph |
| 11:30 – 12:30 | Round table: New sepsis definition: global relevance and tradeoffs | Moderator: Regina Grigolli Debaters: Lúcio Lima, Cláudio Flauzino, Ana Paula Carlotti |
| 12:30 – 14:00 | LUNCH | |
| 12:30 – 13:30 | Sponsors symposium | |
| 14:00 – 14:30 | Conference: Phoenix Sepsis Criteria: How do we implement them at the bedside? | Moderator: Cláudio Flauzino Conferencist: Adrienne Randolph |
| 14:30 – 15:00 | PRO-CON: Septic Shock Management I | Moderator: Maria Helena Dittrich |
| 14:30 – 14:45 | Steroids in Septic Shock: Supporting Recovery When First-Line Fails | José Colleti |
| 14:45 – 15:00 | Steroids for septic shock: rarely meeded and likely harmful | Ana Paula Carlotti |
| 15:00 – 15:15 | Discussion | |
| 15:15 – 16:00 | PRO-CON: Septic Shock Management II | Moderators: Eliana Giorno |
| 15:15 – 15:30 | Echocardiograms by POCUS should be standard | Fábio Jolly |
| 15:30 – 15:45 | POCUS: Echocardiograms by non-cardiologist can be risk | Flávia Foronda |
| 15:45 – 16:00 | Discussion | |
| 16:00 – 16:15 | Interview: Pediatric Sepsis: Epidemiological Perspectives from Latin America, Spain, and Portugal | Interviewer: Milena de Paulis Interviewee: Daniela Souza |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 18:00 | Thematic session: Sepsis prevention, early detection and treatment | Moderadors: Regina Grigolli and Flávia Foronda |
| 16:45 – 17:00 | Effectiveness of vaccination in preventing sepsis | Adrienne Randolph |
| 17:00 – 17:15 | Sepsis Biomarkers: Clinical Insights and Applications | Lúcio Lima |
| 17:15 – 17:30 | Fluids: How much, over what time, what type | Tiago Souza |
| 17:30 – 17:45 | Early use of vasopressors – update on feasibility study | Cláudio Flauzino |
| 17:45 – 18:00 | Discussion | |
| May 23rd – Friday -Room 1 – Adults – clinical track | ||
| 08:30 – 09:00 | Conference: When should we have Sepsis-4, and what should it look like? | Moderator: Rafael Moraes Conferencist: Mervyn Singer |
| 09:00 – 10:15 | Thematic session : Shock persists after 24 hours: what next? | Moderators: Leandro Taniguchi and Carla Pontes |
| 09:00 – 09:15 | Precision medicine with longitudinal shock phenotypes | Mervyn Singer |
| 09:15 – 09:30 | Echocardiography: beyond the basics (discuss uncoupling, LV outflow obstruction) | Livia Melro |
| 09:30 – 09:45 | Deaccumulation of fluids | Flavia Machado |
| 09:45 – 10:00 | Modulating the dysregulated immune response | Manu Shankar-Hari |
| 10:00 – 10:30 | Discussion | |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 12:30 | Thematic session : The shock is over: why is my patient … | Moderators: Roberta Roepke and Felipe da Pizzol |
| 11:00 – 11:15 | Not awake? | Felipe Dal Pizzol |
| 11:15 – 11:30 | Still requiring mechanical ventilation? | Juliana Ferreira |
| 11:30 – 11:45 | Not tolerating tube feeds? | John Marshall |
| 11:45 – 12:00 | Not making urine? | Leandro Taniguchi |
| 12:00 – 12:30 | Discussion | |
| 12:30 – 14:00 | LUNCH | |
| 12:30 – 13:30 | Pfizer Satellite Symposium: Details make the difference: best practices in sepsis management SEE SYMPOSIUM
| Regis Rosa |
| 14:00 – 15:00 | Thematic session: Where are we in 2025: challenges in infectology | Moderators: Matias Salomão and Reinaldo Salomão |
| 14:00 – 14:15 | The use of panels for etiological diagnosis | Marinês Martino |
| 14:15 – 14:30 | Candidemia in ICU Patients: What Are the Real Game-Changers for Survival? | Bianca Almeida |
| 14:30 – 14:45 | Invasive aspergillosis in critically ill patients: how to increase awareness and treat earlier | Marcello Magri |
| 14:45 – 15:00 – | Discussion | |
| 15:00 – 15:45 | Round table: Improving survivorship from ED admission | Moderator: Alexandre Biasi Debaters: Regis Rosa, Derek Angus, Alessandre Guimarães, Diptesh Aryal |
| 15:45 – 16:15 | Conference: AI-driven healthcare – promise and reality | Moderator: Viviane veiga Conferencist: Derek Angus |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 18:25 | GRAND FINALE – the sepsis pipeline | Moderators: Rafael Moraes and Luciano Azevedo |
| 16:45 – 17:00 | Optimal Vasopressin Initiation in Septic Shock: The OVISS Study | Cristopher Seymour |
| 17:00 – 17:10 | Discussion | |
| 17:10 – 17:25 | NOVA trial – a contribution from BRICNET | Bruno Tomazini |
| 17:25 – 17:35 | Discussion | |
| 17:35 – 17:50 | VACIRISS | Manu Shankar-Hari |
| 17:50 – 18:00 | Discussion | |
| 18:00 – 15:15 | Spiral: mechanical ventilation in Latin America | Juliana Ferreira |
| 18:15 – 18:25 | Discussion | |
| May 23rd – Friday – Room 2 – Adults – clinical + multiprofessional track | ||
| 08:30 – 09:00 | Conference: Re-examining the Host Response Hypothesis 30 years later | Moderator: Felipe Dal Pizzol Conferencist: Thierry Calandra |
| 09:00 – 10:00 | Thematic session : How can we improve engament of the heathcare team? | Moderators: Larissa Pellozo and Josiane Ferreira |
| 09:00 – 09:15 | Multidisciplinar training: what are the challenges | Henrique Moura |
| 09:15 – 09:30 | Nursing team: what can be done in the long term | Elaine Valias |
| 09:30 – 09:45 | The patients perspective | Ellen Cumpri |
| 09:45 – 10:00 | Discussion | |
| 10:00 – 10:30 | Clinical challenge: how to improve long term outcomes | Moderator: Bruno Besen Speaker: Regis Rosa |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 11:40 | Oral presentations – Área Clínica | Thiago lisboa and Jorge Salluh |
| 11:40 – 12:30 | Round table: What does ‘good’ quality improvement look like? Is it research? What ethical oversight does it require? | Moderator: Flávia Machado Debaters: Jorge Salluh, Kathy Rowan, Christopher Seymour |
| 12:30 – 14:00 | LUNCH | |
| 14:00 – 15:00 | Thematic session : Thinking out of the box | Moderators: Cintia Grion and Thiago Lisboa |
| 14:00 – 14:15 | Can we go greener in sepsis care? | Rodrigo Henriques |
| 14:15 – 14:30 | Is the AI clinician our future? | Christopher Seymour |
| 14:30 – 14:45 | Reverse innovation: how creative solutions in low-resource settings will alter ICU care for everyone | Diptesh Aryal |
| 14:45 – 15:00 – | Discussion | |
| 15:00 – 15:25 | Challeging images: interactive session | Moderator: Raysa Schmidt Speaker: Pedro Mendes |
| 15:25 – 15:45 | Your question is my question | Juliana Ferreira and Bruno Besen |
| 15:45 – 16:15 | Conference: Revisiting organ dysfunction | Moderator: Rafael Moraes Conferencist: Christopher Seymour |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 18:00 | GRAND FINALE (room 1) | |
| May 23rd – Friday – Room 3 – Pediatrics and translational science | ||
| 08:30 – 09:00 | plenaries in room 1 and 2 | |
| 09:00 – 10:30 | Thematic session: Understanding the microbiota | Moderators: Alexandre Steiner and Patricia Bozza |
| 09:00 – 09:15 | The gut microbiome in critical illness | John Marshall |
| 09:15 – 09:30 | Empirical antibiotic therapy for sepsis: protect the anaerobic microbiota! | Joost Wiersinga |
| 09:30 – 09:45 | Microbiota-Gut-Brain axis in sepsis | Felipe dal Pizzol |
| 09:45 – 10:00 | Molecular insights of microbiota and innate lymphoid cell interactions | Niels Olsen |
| 10:00 – 10:30 | Discussion | |
| 10:30 – 11:00 | BREAK | |
| 11:00 – 11:40 | Oral presentations – Área Básica (20 min para transição de sala ped) | Ana Claudia Torrecilhasand Fernando Cunha |
| 12:00 – 12:30 | Conference: Sepsis trials in children – challenges and opportunities | Moderator: José Colleti Conferencist: Adrienne Randolph |
| 12:30 – 14:00 | LUNCH | |
| 14:00 – 14:45 | Thematic session: Improving sepsis outcomes | Moderator: Marcelo Brandão |
| 14:00- 14::15 | Early recognition of sepsis in the community | Haroldo Carvalho |
| 14:15 – 14:30 | Sepsis protocol: Does it matter? | Daniela Souza |
| 14:30 – 14:45 | Discussion | |
| 14:45 – 15:15 | Clinical challenge: Still in shock: Navigating the next steps | Lúcio Lima |
| 15:15 – 16:15 | Thematic session: Immunometabolism | Moderators: Thierry Calandra and John Marshall |
| 15:15 – 15:30 | Metabolic regulation of immune function | Reinaldo Salomão |
| 15:30 – 15:45 | Rationale for cholesterol supplementation in sepsis | Mervyn Singer |
| 15:45 – 16:00 | Lipid metabolism in sepsis and organ dysfunction | Patrícia Bozza |
| 16:00 – 16:15 | Discussion | |
| 16:15 – 16:45 | BREAK | |
| 16:45 – 18:00 | GRAND FINALE (room 1) | |
